Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
[11C](+)-3-MPB
- Development stage
- Unknown
- Lead developer
- Hamamatsu Photonics
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Small Molecules
- Administration
- Intravenous
01
Overview
[11C](+)-3-MPB (also known as (+)N-[11C]methyl-3-piperidyl benzilate) is a carbon-11 labeled radiopharmaceutical developed as a positron emission tomography (PET) imaging agent. It acts as a non-selective antagonist of muscarinic acetylcholine receptors (mAChRs) in the brain. Developed by researchers at the Research Institute for Brain and Blood Vessels Akita and Hamamatsu Photonics, [11C](+)-3-MPB is used in preclinical and clinical research to evaluate central muscarinic receptor density, occupancy by therapeutic agents (such as scopolamine, oxybutynin, and solifenacin), and alterations in cholinergic system function associated with aging, chronic fatigue syndrome (CFS), and other neurological or psychiatric disorders.
- Other names
- (+)N-[11C]methyl-3-piperidyl benzilate[11C](+)3-MPB
02
Targets
mAChR (Muscarinic acetylcholine receptors)
Beyond the preview
Go deeper on [11C](+)-3-MPB.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on [11C](+)-3-MPB.